What is Piperine?
Piprine is derived from peppercorns from the Piper nigrum, a plant that flowers peppercorns. The unripe peppercorns are dried and cooked to make black pepper. Piperine is the primary bioactive component in black pepper.
Piperine is most commonly used to enhance bioavailability of other supplements, most famously, curcumin. Research has found that a piperine supplement may increase the bioavailability of curcumin by as much as 2000% from baseline levels. Piperine is able to achieve this by inhibiting or downregulating inhibiting phase II detoxification enzymes as well as the glucuronidation process in the liver. Glucuronidation attaches a glucuronide molecule to compounds so that they can be excreted through the urine. Piperine inhibits this process which may lead to elevated levels of certain compounds in the blood.
By inhibiting the detoxifying enzymes, the bioavailability of compounds already in the system is increased. Piperine may slow intestinal transit rate which can increase overall absorption. This may prolong the time compounds are exposed to potential uptake. Piperine also prevents Monoamine oxidase from removing neurotransmitters from the brain, leaving these neurotransmitters open to stimulate brain cells.
Piperine Uses and Benefits
-Promotes bioavailability of dietary supplements
-Promotes digestive health
Piperine in Black Pepper
Piperine is naturally found in the Piper Nigrum plant which produces white and black pepper. Black pepper carries the bioactive compound known as piperine, which is also responsible for black pepper’s distinct taste. Piperine is sometimes referred to as pepperine or black pepper extract.
Piperine is believed to be responsible for black pepper’s properties in supporting gastrointestinal comfort.
Piperine Capsules | 10mg
Increases Bioavailability of Dietary Supplements
Pairs well with Curcumin Powder or Curcumin Capsules
In-house lab tested for product purity and identity